| # | Building | Images | Height | Floors | Building type | Year | Status |
|---|---|---|---|---|---|---|---|
| 1 | Millennium Tower | 1,211 ft | 97 | skyscraper | - | ||
| 2 | Tower 185 | 81 | 669 ft | 55 | skyscraper | 2011 | |
| 3 | ONE | 1 | 627 ft | 49 | skyscraper | 2022 | |
| 4 | Grand Tower | 7 | 590 ft | 48 | skyscraper | 2020 | |
| 5 | Hochaus ehem. Polizeipräsidium | 574 ft | 47 | skyscraper | - | ||
| 6 | Hochhaus Güterplatz | 525 ft | 45 | skyscraper | - | ||
| 7 | Pollux | 28 | 427 ft | 33 | skyscraper | 1999 | |
| 8 | Hochhaus Matthäuskirche | 427 ft | - | skyscraper | - | ||
| 9 | The Spin | 1 | 420 ft | 31 | skyscraper | 2022 | |
| 10 | Grand Hyatt Hotel | 371 ft | 30 | skyscraper | 2013 | ||
| 11 | Hafenstraße-Turm III | 328 ft | - | skyscraper | - | ||
| 12 | Hafenstraße-Turm II | 328 ft | - | skyscraper | - | ||
| 13 | Hafenstraße-Turm I | 328 ft | - | skyscraper | - | ||
| 14 | Eden | 322 ft | 28 | high-rise building | 2021 | ||
| 15 | Kastor | 22 | 312 ft | 22 | high-rise building | 1997 | |
| 16 | Bürohochhaus Commerzbank Trading Center | 2 | 305 ft | 22 | high-rise building | 1976 | |
| 17 | Porsche Design Tower | 262 ft | 24 | high-rise building | - | ||
| 18 | Deutsche Bahn I | 246 ft | 19 | high-rise building | - | ||
| 19 | Deutsche Bahn AG | 2 | 223 ft | 17 | high-rise building | 1993 | |
| 20 | Praedium | 1 | 217 ft | 19 | high-rise building | 2017 |